1150102-89-8Relevant academic research and scientific papers
The first total synthesis of pectinolides D and e and total synthesis of pectinolides A and C
Sabitha, Gowravaram,Ankireddy, Praveen,Das, Sukant Kishore
, (2015/01/08)
The first total synthesis of pectinolides D and E and total synthesis of pectinolides A and C was achieved from a hitherto unknown common key building block prepared from readily available d-mannitol. Key reactions involved in the synthesis are Red-Al reduction of an epoxy alcohol, enantioselective Noyori reduction of ynones, aldehyde-alkyne coupling, and Still-Genari cis-olefination.
Stereoselective synthesis of (2S,3S)-3-hydroxy-2-phenylpiperidine from d-mannitol
Venkataiah, Mallam,Venkateswara Rao,Fadnavis, Nitin W.
experimental part, p. 198 - 201 (2009/07/04)
A novel stereoselective synthesis of N-Boc-(2S,3S)-3-hydroxy-2-phenylpiperidine was achieved from d-mannitol involving the highly stereoselective addition of phenyl Grignard to an allyl imine (de >98%) and ring-closing metathesis (RCM) in the key steps.
