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1150106-13-0

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1150106-13-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1150106-13-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,1,0 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1150106-13:
(9*1)+(8*1)+(7*5)+(6*0)+(5*1)+(4*0)+(3*6)+(2*1)+(1*3)=80
80 % 10 = 0
So 1150106-13-0 is a valid CAS Registry Number.

1150106-13-0Downstream Products

1150106-13-0Relevant academic research and scientific papers

Design and synthesis of inhibitors of hedgehog signaling based on the alkaloid cyclopamine

Winkler, Jeffrey D.,Isaacs, Andre,Holderbaum, Laura,Tatard, Valerie,Dahmane, Nadia

, p. 2824 - 2827 (2009)

The synthesis and biological evaluation of structurally simplified, metabolically stable cyclopamine-like Sonic Hedgehog (SHH) signaling inhibitors, i.e., 5, is described in four chemical steps from commercially available steroidal precursors. Biological

STEROID-DERIVED CYCLOPAMINE ANALOGS AND METHODS FOR USING THE SAME IN THE PREVENTION OR TREATMENT OF CANCER

-

Page/Page column 10; 28, (2009/06/27)

The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided.

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