115012-47-0 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-chlorophenyl)piperidin-4-one is used as a key intermediate in the synthesis of pharmaceuticals for its versatile chemical reactivity and potential pharmacological properties. Its ability to be modified and incorporated into complex molecular structures makes it an essential component in the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(2-chlorophenyl)piperidin-4-one is utilized as a valuable building block for the creation of various organic compounds. Its unique structure allows for multiple points of attachment and modification, facilitating the synthesis of a wide range of molecules with diverse applications.
Used in Research and Development:
1-(2-chlorophenyl)piperidin-4-one is also used in research and development settings to study its potential pharmacological properties, particularly its effects on the central nervous system. This research aims to uncover new therapeutic applications and understand the compound's mechanisms of action, which could lead to the development of novel treatments for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 115012-47-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,0,1 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 115012-47:
(8*1)+(7*1)+(6*5)+(5*0)+(4*1)+(3*2)+(2*4)+(1*7)=70
70 % 10 = 0
So 115012-47-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H12ClNO/c12-10-3-1-2-4-11(10)13-7-5-9(14)6-8-13/h1-4H,5-8H2
115012-47-0Relevant academic research and scientific papers
Some observations relating to the use of 1-aryl-4-alkoxypiperidin-4-yl groups for the protection of the 2′-hydroxy functions in the chemical synthesis of oligoribonucleotides
Lloyd, Wayne,Reese, Colin B.,Song, Quanlai,Vandersteen, Anthony M.,Visintin, Cristina,Zhang, Pei-Zhou
, p. 165 - 176 (2007/10/03)
The comparative rates of acid-catalysed removal often 1-aryl-4-methoxypiperidin-4-yl 8 (R = Me) [including the previously reported Ctmp 5 and Fpmp 6] protecting groups for the 2′-hydroxy functions in oligoribonucleotide synthesis are discussed. These studies have led to the development of the 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl (Cpep) protecting group 8 (R = Et, R1 = R2 = H, R3 = Cl) which is both more stable than the Ctmp and Fpmp groups at pH 0.5 and more labile at pH 3.75. The influence of the ribonucleoside aglycone on the stability of the 2′-O-Fpmp and 2′-O-Ctmp protecting groups both at low and high pH is examined. The Royal Society of Chemistry 2000.
