1150209-03-2Relevant academic research and scientific papers
Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors
Schweinitz, Andrea,Doennecke, Daniel,Ludwig, Alexander,Steinmetzer, Peter,Schulze, Alexander,Kotthaus, Joscha,Wein, Silvia,Clement, Bernd,Steinmetzer, Torsten
, p. 1960 - 1965 (2009)
A novel series of matriptase inhibitors based on previously identified tribasic 3-amidinophenylalanine derivatives was prepared. The C-terminal basic group was replaced by neutral residues to reduce the hydrophilicity of the inhibitors. The most potent co
