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1150248-80-8

1150248-80-8

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1150248-80-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1150248-80-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,2,4 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1150248-80:
(9*1)+(8*1)+(7*5)+(6*0)+(5*2)+(4*4)+(3*8)+(2*8)+(1*0)=118
118 % 10 = 8
So 1150248-80-8 is a valid CAS Registry Number.

1150248-80-8Downstream Products

1150248-80-8Relevant articles and documents

Liver X receptor agonists with selectivity for LXRβ; N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides

Swahn, Britt-Marie,Macsari, Istvan,Viklund, Jenny,Oehberg, Liselotte,Sjoedin, Johanna,Neelissen, Jan,Lindquist, Johanna

scheme or table, p. 2009 - 2012 (2009/11/30)

The synthesis and SAR of a new series of LXR agonist is reported. The N-Aryl-3,3,3-trifluoro-2-hydroxy-2-methyl-propionamide hits were found in a limited screen of the AstraZeneca compound collection. The effort to optimize these hits into LXRβ selectivity is described. Compound 20 displayed desirable pharmacokinetic profile and up regulation of ABCA1 and ABCG1 mRNA in the brain were achieved when evaluated in vivo in mice.

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