1150310-11-4

Basic information

• Product Name: C₁₇H₁₃N₃O₆
• Synonyms: C₁₇H₁₃N₃O₆
• CAS NO: 1150310-11-4
• Molecular Weight: 355.307
• Mol File: 1150310-11-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₃N₃O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₃N₃O₆(1150310-11-4)
• EPA Substance Registry System: C₁₇H₁₃N₃O₆(1150310-11-4)

Safety Data

• Hazardous Substances Data: 1150310-11-4(Hazardous Substances Data)

Upstream product

• 5382-38-7 2-cyano-N-(4-methoxyphenyl)acetamide 
• 116313-85-0 3,4-dihydroxy-5-nitrobenzaldehyde 

Relevant articles and documents

The synthesis and biological evaluation of some caffeic acid amide derivatives: E-2-Cyano-(3-substituted phenyl)acrylamides

A series of caffeic acid amide derivatives 2-cyano-(3-substituted phenyl)acrylamides were synthesized via Knoevenogal condensation of substituted benzaldehydes with cyanoacetamides. The structure of compound 1f was determined as E-isomer by X-ray diffractive analysis. The biological screening tests in vitro showed that compound 1b has obvious inhibitory activities against human gastric carcinoma cell line BGC-823, human nasopharyngeal carcinoma cell line KB and human hepatoma cell line BEL-7402 with IC50 values of 5.6 μg/mL, 13.1 μg/mL and 12.5 μg/mL, respectively. Some preliminary structure-activity relationships (SAR) were also proposed which may provide a direction for further study.