115149-47-8

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 

Downstream Products

• 115149-55-8 methyl 2-(3-aminopropoxy)-5-chlorobenzoate hydrochloride 
• 115149-61-6 N-<3-(2-carboxy-4-chlorophenoxy)propyl>-m-hydroxyphenylacetamide 
• 115149-58-1 N-<3-(4-chloro-2-methoxycarbonylphenoxy)propyl>-m-hydroxyphenylacetamide 

Relevant academic research and scientific papers

BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION

The invention concerns benzodiazepine derivatives of Formula (I) wherein W, X, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment or prophylaxis of hepatitis C virus infection.

SYNTHESIS OF NOVEL MACROCYCLIC LACTONES WITH POTENTIAL PHARMACOLOGICAL ACTIVITY

The total syntheses of four 14-membered ring lactones, (1a), (2a), (22), and (23), are described.The starting materials are the appropriate 2-hydroxybenzoic or (2-hydroxyphenyl)acetic acids and the final step in each case involves lactonization using a mo