1151513-01-7

Basic information

• Product Name: tert-butyl (5-(2-benzyl-2H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methylcarbamate
• Synonyms: tert-butyl (5-(2-benzyl-2H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methylcarbamate
• CAS NO: 1151513-01-7
• Molecular Weight: 405.456
• Mol File: 1151513-01-7.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl (5-(2-benzyl-2H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (5-(2-benzyl-2H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methylcarbamate(1151513-01-7)
• EPA Substance Registry System: tert-butyl (5-(2-benzyl-2H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methylcarbamate(1151513-01-7)

Safety Data

• Hazardous Substances Data: 1151513-01-7(Hazardous Substances Data)

Upstream product

• 1151512-98-9 3-[3-tert-butoxycarbonylaminomethyl-1,2,4-oxadiazol-5-yl]indazole 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1151513-25-5 CFM₆₀₅₈ 

Relevant articles and documents

Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis

A series of imidazol-1-ylethylindazole sodium channel ligands were developed and optimized for sodium channel inhibition and in vitro neuroprotective activity the molecules exhibited displacement of a radiolabeled sodium channel ligand and selectivity for blockade of the inactivated state of cloned neuronal Nav channels. Metabolically stable analogue 6 was able to protect retinal ganglion cells during optic neuritis in a mouse model of multiple sclerosis.

Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones

We report the discovery of a new class of neuroprotective voltage-dependent sodium channel modulators exemplified by (5-(1-benzyl-1H-indazol-3-yl)-1,2,4- oxadiazol-3-yl)methanamine 11 (CFM1178). The compounds were inhibitors of [ 14C]guanidiniu