1151561-96-4Relevant academic research and scientific papers
An interrupted Ugi reaction enables the preparation of substituted indoxyls and aminoindoles
Schneekloth, John S.,Kim, Jr., Jimin,Sorensen, Erik J.
experimental part, p. 3096 - 3101 (2009/09/05)
In a variation of the classical Ugi reaction, an acid-promoted reaction between imines and isocyanides forms both 3-aminoindoles and substituted indoxyls. A recently reported triflyl phosphoramide is shown to be critical to obtain high yields under mild c
