1151788-45-2Relevant academic research and scientific papers
Fragment-Based Identification of Influenza Endonuclease Inhibitors
Credille, Cy V.,Chen, Yao,Cohen, Seth M.
supporting information, p. 6444 - 6454 (2016/07/26)
The influenza virus is responsible for millions of cases of severe illness annually. Yearly variance in the effectiveness of vaccination, coupled with emerging drug resistance, necessitates the development of new drugs to treat influenza infections. One a
Synthesis of hydroxypyrone- and hydroxythiopyrone-based matrix metalloproteinase inhibitors: Developing a structure-activity relationship
Yan, Yi-Long,Miller, Melissa T.,Cao, Yuchen,Cohen, Seth M.
supporting information; experimental part, p. 1970 - 1976 (2009/11/30)
The zinc(II)-dependent matrix metalloproteinases (MMPs) are associated with a variety of diseases. Development of inhibitors to modulate MMP activity has been an active area of investigation for therapeutic development. Hydroxypyrones and hydroxythiopyron
