1152001-02-9Relevant academic research and scientific papers
Highly regioselective heck coupling reactions of aryl halides and dihydropyran in the presence of an NHC-pyridine ligand
Jarusiewicz, Jamiei,Kyung, Soo Yoo,Kyung, Woon Jung
experimental part, p. 482 - 486 (2009/08/09)
The Heck coupling reactions of aryl halides and 3,4-dihydro-2H-pyran facilitated the regioselective synthesis of arylated cyclic enol ethers. Good yields were obtained using 5 mol% of an NHC-ligand-Pd-catalyst complex in the presence of K2CO3 in DMF at 100°C. The use of this catalytic system broadens the substrate scope and improves the selectivity for this cross-coupling process. Georg Thieme Verlag Stuttgart.
