115215-89-9

Basic information

• Product Name: 5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one
• CAS NO: 115215-89-9
• Molecular Weight: 150.18
• Mol File: 115215-89-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 360.4±11.0 °C(Predicted)
• Density: 1.230±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one(115215-89-9)
• EPA Substance Registry System: 5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one(115215-89-9)

Safety Data

• Hazardous Substances Data: 115215-89-9(Hazardous Substances Data)

Upstream product

• 499206-24-5 2-((dimethylamino)methylene)cycloheptane-1,3-dione 
• 1194-18-9 cycloheptane-1,3-dione 
• 623-73-4 diazoacetic acid ethyl ester 
• 85302-16-5 1-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indazole 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 1235325-16-2 pyridin-2-yl-(4,5,6,8-tetrahydro-3-thia-1,7,8-triaza-cyclopenta[e]azulen-2-yl)-amine 
• 1314140-32-3 8-(4-methoxybenzyl)-4,5,6,8-tetrahydro-3-thia-1,7,8-triazacyclopenta[e]azulen-2-ylamine 
• 1314139-89-3 5-bromo-2-(4-methoxybenzyl)-5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one 
• 1314140-29-8 2-(4-methoxybenzyl)-5,6,7,8-tetrahydro-2H-cycloheptapyrazol-4-one 

Relevant articles and documents

Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators

There is an increasing amount of evidence to support that activation of the metabotropic glutamate receptor 4 (mGlu4 receptor), either with an orthosteric agonist or a positive allosteric modulator (PAM), provides impactful interventions in diseases such as Parkinson's disease, anxiety, and pain. mGlu4 PAMs may have several advantages over mGlu4 agonists for a number of reasons. As part of our efforts in identifying therapeutics for central nervous system (CNS) diseases such as Parkinson's disease, we have been focusing on metabotropic glutamate receptors. Herein we report our studies with a series of tricyclic thiazolopyrazoles as mGlu4 PAMs.

Cycloalkane[1,2-c:4,3-c']dipyrazoles and their use as bronchodilators

The present invention is directed to a group of methylated tetrahydro cyclohepta[1,2-c:4,3-c']dipyrazoles and benzo[1,2-c:4,3-c']dipyrazoles useful as bronchodilators. The compounds are prepared by the reaction of an appropriate hydrazine with an appropri