115216-95-0

Upstream product

• 119259-01-7 5-(1(R)-hydroxy-7-(trimethylsilyl)-2,4,6-heptatriynyl)-2-oxo-4(S),5(S)-1,3-dioxolane-4-heptanoic acid, methyl ester 
• 30043-41-5 (hex-5-enyl)magnesium bromide 
• 131425-26-8 7-[(4R,5S,4'S,5'R)-5'-(Bis-ethylsulfanyl-methyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl]-heptanoic acid ethyl ester 
• 131425-23-5 (S)-1-((3aR,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-hept-6-en-1-ol 
• 131442-99-4 7-{(4S,5R)-5-[(R)-1-(4-Methoxy-benzyloxy)-7-trimethylsilanyl-hepta-2,4,6-triynyl]-2-oxo-[1,3]dioxolan-4-yl}-heptanoic acid methyl ester 
• 131442-98-3 7-{(4S,5R)-5-[(R)-1-(4-Methoxy-benzyloxy)-prop-2-ynyl]-2-oxo-[1,3]dioxolan-4-yl}-heptanoic acid methyl ester 
• 131425-25-7 (E)-(S)-8-((3aR,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-hydroxy-oct-2-enoic acid ethyl ester 
• 131442-97-2 7-{(4S,5R)-5-[(R)-1-(4-Methoxy-benzyloxy)-prop-2-ynyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-heptanoic acid 
• 131425-33-7 (8S,9R,10R)-8,9-Dihydroxy-10-(4-methoxy-benzyloxy)-dodec-11-ynoic acid methyl ester 
• 131425-24-6 (S)-6-((3aR,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-6-hydroxy-hexanal 
• 131425-27-9 7-((4R,5S,4'R,5'S)-5'-Hydroxymethyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-heptanoic acid ethyl ester 
• 131425-28-0 7-((4R,5S,4'S,5'R)-5'-Chloromethyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-heptanoic acid ethyl ester 
• 131442-96-1 7-((4R,5S,4'S,5'R)-5'-Chloromethyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-heptanoic acid 
• 131425-30-4 (S)-8-Hydroxy-8-((3aR,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-octanoic acid ethyl ester 

Relevant academic research and scientific papers

Total synthesis of triyne carbonate L-660,631 methylester from D-glucose

A stereocontrolled synthesis of methylester of triyne carbonate L-660,631, a new anti-fungal agent, is described starting from D-glucose.

SYNTHESIS OF L-660,631 METHYL ESTER AND RELATED COMPOUNDS

Triyne carbonate L-660,631 methyl ester (2) was synthesized in eight steps from cyclooctene.Synthetic methodology to permit systematic variation of the triyne portion of the molecule has been developed.