1152162-39-4 Usage
Description
(E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one, also known as (E)-1-(4-fluorophenyl)-3-(4-benzyloxyphenyl)prop-2-en-1-one, is a chemical compound characterized by its prop-2-en-1-one backbone with a 4-fluorophenyl and a benzyloxyphenyl substituent. (E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one is recognized for its potential pharmacological properties and is frequently utilized in organic synthesis and drug development. Its unique structure and properties also contribute to its value in studying chemical reactions and mechanisms, making it a significant compound in the realms of organic chemistry and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one is used as a key intermediate in the synthesis of various pharmaceutical compounds for the treatment of different diseases and conditions. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Organic Synthesis:
In the field of organic chemistry, (E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one serves as a versatile building block for the creation of more complex molecules. Its reactivity and structural features make it a valuable component in the synthesis of a wide range of organic compounds.
Used in Chemical Reaction Studies:
(E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one is also utilized as a model system for studying various chemical reactions and mechanisms. Understanding how (E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one interacts with other molecules can provide insights into fundamental chemical processes and potentially lead to the discovery of new reaction pathways.
Overall, (E)-3-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)prop-2-en-1-one is a multifaceted compound with applications spanning across pharmaceutical research, organic synthesis, and chemical reaction studies, showcasing its importance in the broader context of chemical and pharmaceutical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 1152162-39-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,2,1,6 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1152162-39:
(9*1)+(8*1)+(7*5)+(6*2)+(5*1)+(4*6)+(3*2)+(2*3)+(1*9)=114
114 % 10 = 4
So 1152162-39-4 is a valid CAS Registry Number.
1152162-39-4Relevant articles and documents
Chalcones: A valid scaffold for monoamine oxidases inhibitors
Chimenti, Franco,Fioravanti, Rossella,Bolasco, Adriana,Chimenti, Paola,Secci, Daniela,Rossi, Francesca,Yá?ez, Matilde,Orallo, Francisco,Ortuso, Francesco,Alcaro, Stefano
supporting information; experimental part, p. 2818 - 2824 (2010/01/16)
A large series of substituted chalcones have been synthesized and tested in vitro for their ability to inhibit human monoamine oxidases A and B (hMAO-A and hMAO-B). While all the compounds showed hMAO-B selective activity in the micro- and nanomolar ranges, the best results were obtained in the presence of chlorine and hydroxyl or methoxyl substituents. To better understand the enzyme-inhibitor interaction and to explain the selectivity of the most active compounds toward hMAO-B, molecular modeling studies were carried out on new, high resolution, hMAO-B crystallographic structures. For the only compound that also showed activity against hMAO-A as well as low selectivity, the molecular modeling study was also performed on the hMAO-A crystallographic structure. The docking technique provided new insight on the inhibition mechanism and the rational drug design of more potent/selective hMAO inhibitors based on the chalcone scaffold.
