1152166-56-7Relevant articles and documents
The proline-catalyzed double Mannich reaction of acetaldehyde with N-Boc imines
Chandler, Carley,Galzerano, Patrizia,Michrowska, Anna,List, Benjamin
supporting information; experimental part, p. 1978 - 1980 (2009/07/25)
(Chemical Equation Presented) Double-cross: Proline catalyzes the double Mannich reaction of acetaldehyde with N-Boc imines in excellent yields (up to 99%; Boc = tert-butoxycarbonyl) and close to perfect diastereo- and enantioselectivities. Depending on t