115224-32-3

Upstream product

• 115224-31-2 1-((1R,4R,5R)-4,5-Dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-4-methylsulfanyl-1H-pyrimidin-2-one 
• 115150-09-9 1-<(1R,2R,3R)-2,2'-anhydro-3-hydroxy-4-hydroxymethyl-4-cyclopenten-1-yl>-4(1H)-pyrimidinone 
• 1203458-34-7 C₂₄H₄₃N₃O₄Si₂ 
• 90597-20-9 1-<(1R,2S,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl>-2,4-(1H,3H)-pyrimidinedione 
• 115224-30-1 1-<(1R,2R,3R)-2,3-diacetoxy-4-acetoxymethyl-4-cyclopenten-1-yl>-4-thio-2(1H,3H)-pyrimidinone 
• 115224-29-8 1-<(1R,2R,3R)-2,3-diacetoxy-4-acetoxymethyl-4-cyclopenten-1-yl>-2,4(1H,3H)-pyrimidinedione 
• 115224-28-7 1-<(1R,2R,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl>-2,4(1H,3H)-pyrimidinedione 
• 115150-05-5 Imidazole-1-carbothioic acid O-[(2R,3S,3aR)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-5,5,7,7-tetraisopropyl-2,3,3a,9-tetrahydro-4,6,8-trioxa-5,7-disila-cyclopentacycloocten-3-yl] ester 
• 115166-42-2 1-<(1R,2S,3R)-2-hydroxy-3,6-O-(tetraisopropyldisiloxane-1,3-diyl)-4-cyclopenten-1-yl>-2,4-(1H,3H)-pyrimidinedione 
• 115166-43-3 1-<(1R,2R,3R)-2-2'-anhydro-3,6-O-(tetraisopropyldisiloxane-1,3-diyl)-4-cyclopenten-1-yl>-4(1H)-pyrimidinone 
• 90597-18-5 (1R,2S,3R)-1--2,3-isopropylidenedioxy-4-methoxymethyloxymethyl-4-cyclopentene 
• 90597-19-6 1-<(1R,2S,3R)-2,3-isopropylidenedioxy-4-methoxymethyloxymethyl-4-cyclopenten-1-yl>-2,4-(1H,3H)-pyrimidinedione 

Relevant academic research and scientific papers

A convergent approach for the synthesis of ara-neplanocin a analogues under subzero microwave assisted conditions

A convergent strategy for the synthesis of ara-neplanocin A analogues has been developed. Microwave assisted Mitsunobu reaction proved to be an essential tool both for the 2' - hydroxy inversion and for the coupling reaction with the heterocyclic bases. The exploitation of the present approach allowed generating a family of ara-neplanocins which biological potential is still unexplored.

ENANTIOSELECTIVE SYNTHESIS OF NEW ANALOGS OF NEPLANOCIN A AND THEIR BIOLOGICAL ACTIVITY

Various carbocyclic nucleosides analogs of neplanocin A (such as 5-aminoimidazole-4-carboxamide riboside, uridine, 5-iodouridine, 4-thiouridine, cytidine, thymidine, 2'-deoxyguanosine, ribofuranosylthymine, a 2,2'-anhydroderivative, 2'-deoxycytidine, 2'-d