115229-74-8Relevant academic research and scientific papers
Palladium-Catalyzed Fluoroalkylation via C(sp3)-S Bond Cleavage of Vinylsulfonium Salts
He, Yuan,Huang, Zilong,Ma, Juan,Huang, Fei,Lin, Jie,Wang, Hongmei,Xu, Bao-Hua,Zhou, Yong-Gui,Yu, Zhengkun
, p. 6110 - 6114 (2021)
An interrupted Pummerer/palladium-catalyzed fluoro-alkylation strategy was developed for alkenyl C-H fluoroalkylthiolation. Palladium-catalyzed ring-opening fluoroalkylation via aliphatic C-S bond cleavage of the vinylsulfonium salts efficiently afforded
Iodine-Mediated Copper-Catalyzed Efficient α-C(sp2)-Thiomethylation of α-Oxoketene Dithioacetals with Dimethyl Sulfoxide in One Pot
Shukla, Gaurav,Srivastava, Abhijeet,Nagaraju, Anugula,Raghuvanshi, Keshav,Singh, Maya Shankar
, p. 3969 - 3976 (2016/01/25)
The direct α-Csp2￡H functionalization and thiomethylation of α-oxoketene dithioacetals (DTAs) has been accomplished with dimethyl sulfoxide (DMSO) in the presence of iodine and a copper(I) salt for the first time. A prerequisite is the in situ iodination of the α-Csp2 atom of dithioacetals that could offer other reaction channels. The operationally simple one-pot protocol includes region-defined consecutive iodination and sulfenylation of the challenging α-Csp2￡H bond of dithioacetals employing cheap and readily available reagents. DMSO here plays a dual role as thiomethyl source and solvent.
