1152312-13-4

Basic information

• Product Name: C₃₅H₃₃IN₄O₅
• Synonyms: C₃₅H₃₃IN₄O₅
• CAS NO: 1152312-13-4
• Molecular Weight: 716.575
• Mol File: 1152312-13-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₅H₃₃IN₄O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₅H₃₃IN₄O₅(1152312-13-4)
• EPA Substance Registry System: C₃₅H₃₃IN₄O₅(1152312-13-4)

Safety Data

• Hazardous Substances Data: 1152312-13-4(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 6683-28-9 methyl ((benzyloxy)carbonyl)-L-tryptophyl-L-phenylalaninate 

Downstream Products

• 1152312-14-5 C₆₁H₆₉N₇O₁₁ 

Relevant articles and documents

Scalable total syntheses of N -linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F

This report details the invention of a method to enable syntheses of psychotrimine (1) and the kapakahines F and B (2, 3) on a gram scale and in a minimum number of steps. Mechanistic inquiries are presented for the key enabling quaternization of indole at the C3 position by electrophilic attack of an activated aniline species. Excellent chemo-, regio-, and diastereoselectivities are observed for reactions with o-iodoaniline, an indole cation equivalent. Additionally, the scope of this reaction is broad with respect to the tryptamine and aniline components. The anti-cancer profiles of 1-3 have also been evaluated.