1152508-92-3Relevant academic research and scientific papers
Synthetic N-alkylated iminosugars as new potential immunosuppressive agents
Wang, Guan-Nan,Xiong, Yulan,Ye, Jia,Zhang, Li-He,Ye, Xin-Shan
, p. 682 - 686 (2011)
The new emerging immunosuppressive effects displayed by iminosugars have not been much investigated so far. Several new N-alkyl dideoxy iminoalditols were designed and synthesized to explore their immunosuppressive effects. These iminosugars inhibited the
Rational design and synthesis of highly potent pharmacological chaperones for treatment of N370S mutant Gaucher disease
Wang, Guan-Nan,Reinkensmeier, Gabriele,Zhang, Si-Wei,Zhou, Jian,Zhang, Liang-Ren,Zhang, Li-He,Butters, Terry D.,Ye, Xin-Shan
supporting information; experimental part, p. 3146 - 3149 (2010/03/03)
Highly potent N-substituted δ-lactams have been rationally designed and synthesized by a concise route with a one-pot tandem reaction as key step. These iminosugars show weak inhibition of wildtype β-glucocerebrosidase but 3- to 6-fold increases in mutant
