115255-48-6Relevant academic research and scientific papers
Synthesis of enantiomerically pure [14C]-labelled morpholine derivatives for a class of trace amine-associate receptor 1 agonists
Edelmann, Martin R.,Hartung, Thomas,Trussardi, René,Iding, Hans,Galley, Guido,Pflieger, Philippe,Norcross, Roger D.
, p. 635 - 639 (2016/12/26)
Various agonists of the trace amine-associate receptor 1, under consideration as potential clinical development candidates, were labelled with carbon-14 for use in preclinical in vitro and in vivo drug metabolism studies. Herein, the [14C]-radi
[14C] and [13C] labellings from N-(2-diethylaminoethyl)-4-iodobenzamide, and N-(3-deimethylaminopropyl)-4-iodobenzamide, melanoma tracers
Moreau,Parry,Bayle,Papon,Labarre,Veyre
, p. 805 - 813 (2007/10/02)
N-(2-diethylaminoethyl)-4-iodobenzamide (I) and N-(3-dimethylaminopropyl)-4-iodobenzamide (II), recently developed in our laboratory, are promising agents for metastatic melanoma detection in nuclear medicine. In order to study their 'in vivo' metabolism,
