1152589-49-5

Upstream product

• 1632036-75-9 (R)-2-[(1R,2R)-1-hydroxy-2-(methoxymethoxy)-2-phenylethyl]cyclopentanone 
• 107536-09-4 (2R)-2-methoxymethoxy-3-phenylacetaldehyde 
• 269402-51-9 (R)-2-methyloxymethoxy-2-phenyl-1-ethanol 
• 1632036-78-2 C₁₃H₁₆O₃ 
• 77-76-9 2,2-dimethoxy-propane 
• 1152589-85-9 C₁₆H₂₂O₃ 

Downstream Products

• 1152589-56-4 (R)-6-[(4R,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl]tetrahydropyran-2-one 

Relevant academic research and scientific papers

Synthesis of 7- Epi -goniodiol by proline-catalyzed diastereoselective direct aldol reaction

A simple organocatalytic approach was developed for the total synthesis of 7-epi-goniodiol. The strategy involves l-proline-catalyzed diastereoselective direct aldol reaction and Baeyer-Villiger oxidation as key steps for the construction of chiral lactone. Georg Thieme Verlag Stuttgart New York.

Syntheses of all stereoisomers of goniodiol from yeast-reduction products and their antimicrobiological activity

All stereoisomers of goniodiol were synthesized from yeast-reduction products. The C-6 chiral centers were converted from the chiral centers of the yeast-reduction products. Stereoselective conversion of the alkene, which had been prepared from the yeast-reduction product, to glycol constructed the C-7 and C-8 stereochemistry. (+)-Goniodiol and 7-epi-(+)-goniodiol showed the highest antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia.