1152617-46-3

Usage

Uses

Used in Organic Synthesis:
[2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl-amine is used as a synthetic building block for the creation of more complex organic molecules. Its unique structure, including the cyclopropyl-amine and phenyl groups, allows for a wide range of reactions and the formation of diverse chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl-amine is used as a key intermediate in the development of new drugs. Its structural features can be exploited to design and synthesize novel therapeutic agents with potential applications in various medical conditions.
Used in Chemical Research:
[2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl-amine is also utilized in chemical research as a model system for studying the reactivity and properties of cyclopropyl-amine and phenyl groups. Understanding the behavior of these functional groups can lead to the development of new synthetic methods and the discovery of new chemical reactions.
Used in Material Science:
[2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl-amine may find applications in material science, where its unique structural features can be employed to design and synthesize new materials with specific properties, such as improved stability, reactivity, or selectivity.

Upstream product

• 1152617-42-9 4-bromo-2-chloro-N-cyclopropylaniline 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1152614-91-9 7-(3-chloro-4-cyclopropylaminophenyl)-3-(2,2,2-trifluoroethyl)imidazo[1,2-a]pyridine-8-carbonitrile 

Relevant academic research and scientific papers

7-ARYL-1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

The present invention relates to novel triazolo[4,3-a]pyridine derivatives of Formula (I) wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2"), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.

IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

The present invention relates to novel compounds, in particular novel imidazo[1,2-a]piridine derivatives according to Formula (I) wherein all radicals are as defined in the application and claims. The compounds according to the invention are positive allosteric modulators of metabotropic receptors - subtype 2 ("mGluR2") which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.