115282-41-2 Usage
Uses
Used in Organic Synthesis:
4-DIMETHYLAMINOPHENYLGLYOXAL HYDRATE is used as a reactant in organic synthesis for the preparation of various compounds. Its unique chemical properties make it a valuable component in the synthesis of complex organic molecules.
Used in Research and Laboratory Settings:
In research and laboratory settings, 4-DIMETHYLAMINOPHENYLGLYOXAL HYDRATE is utilized for its potential applications in the development and study of new chemical compounds and reactions. Its reactivity and versatility contribute to the advancement of scientific knowledge and the discovery of novel chemical processes.
Used in Safety and Precautionary Measures:
Due to its potential allergenic and irritating properties, 4-DIMETHYLAMINOPHENYLGLYOXAL HYDRATE is also used as a reminder of the importance of following proper safety protocols and guidelines when working with chemicals. This includes the use of personal protective equipment, handling procedures, and disposal methods to minimize health hazards and ensure safe laboratory practices.
Check Digit Verification of cas no
The CAS Registry Mumber 115282-41-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,2,8 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115282-41:
(8*1)+(7*1)+(6*5)+(5*2)+(4*8)+(3*2)+(2*4)+(1*1)=102
102 % 10 = 2
So 115282-41-2 is a valid CAS Registry Number.
115282-41-2Relevant academic research and scientific papers
Oxalyl-CoA Decarboxylase Enables Nucleophilic One-Carbon Extension of Aldehydes to Chiral α-Hydroxy Acids
Burgener, Simon,Cortina, Ni?a Socorro,Erb, Tobias J.
supporting information, p. 5526 - 5530 (2020/02/20)
The synthesis of complex molecules from simple, renewable carbon units is the goal of a sustainable economy. Here we explored the biocatalytic potential of the thiamine-diphosphate-dependent (ThDP) oxalyl-CoA decarboxylase (OXC)/2-hydroxyacyl-CoA lyase (HACL) superfamily that naturally catalyzes the shortening of acyl-CoA thioester substrates through the release of the C1-unit formyl-CoA. We show that the OXC/HACL superfamily contains promiscuous members that can be reversed to perform nucleophilic C1-extensions of various aldehydes to yield the corresponding 2-hydroxyacyl-CoA thioesters. We improved the catalytic properties of Methylorubrum extorquens OXC by rational enzyme engineering and combined it with two newly described enzymes—a specific oxalyl-CoA synthetase and a 2-hydroxyacyl-CoA thioesterase. This enzymatic cascade enabled continuous conversion of oxalate and aromatic aldehydes into valuable (S)-α-hydroxy acids with enantiomeric excess up to 99 %.
