1152957-31-7

Basic information

• Product Name: 2-morpholino-1-(4-(methyl)phenyl)propan-1-one
• Synonyms: 2-morpholino-1-(4-(methyl)phenyl)propan-1-one
• CAS NO: 1152957-31-7
• Molecular Weight: 233.31
• Mol File: 1152957-31-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-morpholino-1-(4-(methyl)phenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-morpholino-1-(4-(methyl)phenyl)propan-1-one(1152957-31-7)
• EPA Substance Registry System: 2-morpholino-1-(4-(methyl)phenyl)propan-1-one(1152957-31-7)

Safety Data

• Hazardous Substances Data: 1152957-31-7(Hazardous Substances Data)

Upstream product

• 5337-93-9 4'-methylpropiophenone 
• 110-91-8 morpholine 
• 92821-88-0 2-bromo-4'-methylpropiophenone 
• 106-38-7 para-bromotoluene 
• 25574-04-3 1-p-tolyl-1-propanol 

Relevant articles and documents

Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium-f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution

The iridium-f-amphox-catalyzed asymmetric hydrogenation of racemic α-amino β-unfunctionalized ketones proceeds via a DKR (dynamic kinetic resolution) process for the construction of various chiral N,N-disubstituted α-amino β-unfunctionalized alcohols in quantitative yields with excellent enantioselectivities and diastereoselectivities (all products >99% ee and >99:1 dr, TON up to 100 000). Importantly, this catalytic asymmetric hydrogenation with a DKR process provided a highly efficient and powerful synthetic strategy for the preparation of key chiral intermediates of the preclinical antitumor agent (S,S)-R116010.

Copper bromide reagent and its preparation method, α--aminobenzene acetone and its process for synthesis of derivatives of

The invention discloses a copper bromide reagent, a preparation method thereof, and a synthesis method of alpha-amido propiophenone and derivative thereof. Copper bromide cheap in industry and 2,6-bi[4-(1,1-dimethyl)-2-oxazoline-2-base] pyridine react to directly obtain high yield of high-purity copper bromide reagent, in addition, the copper bromide reagent and propiophenone containing multiple important functional groups have good reaction activity. Due to the characteristic, high yield of alpha-amido propiophenone and derivative thereof can be obtained in mild conditions, conventional expensive azoic compound materials are not used, the cost is lowered to a large extent, the operation requirement is also lowered, and alpha-amido propiophenone and derivative thereof have good application prospect in industry.

Synthesis and characterization of bisoxazolines- and pybox-copper(II) complexes and their application in the coupling of α-carbonyls with functionalized amines

Binuclear complexes [{(DMOX)CuCl}2(μ-Cl)2] (1), mononuclear complexes [(DMOX)CuBr2] (2) (DMOX = 4,5-dihydro-2-(4,5- dihydro-4,4-dimethyloxazol-2-yl)-4,4-dimethyloxazole) and the pybox Cu(ii) complex [(Dm-Pybox)CuBr2/