115304-41-1

Upstream product

• 693245-36-2 (3S,4S,5R,6S,7R)-4,5,6,7-tetrahydroxy-1-oxaspiro[2,5]octane 
• 694527-29-2 1L-(1,2,4/3,5)-1-C-(acetoxymethyl)-2,3,4,5-tetra-O-acetyl-1,2,3,4,5-cyclohexanepentol 
• 78963-40-3 2L-(2,4/3,5)-2,3,4,5-tetrahydroxycyclohexan-1-one 
• 488-76-6 (-)-viburnitol 
• 504397-79-9 (1S,2S,3R,5S,6S)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-7-oxa-bicyclo[4.1.0]heptane-2,3,5-triol 

Downstream Products

• 694527-29-2 1L-(1,2,4/3,5)-1-C-(acetoxymethyl)-2,3,4,5-tetra-O-acetyl-1,2,3,4,5-cyclohexanepentol 

Relevant academic research and scientific papers

Convenient synthesis of (+)-valiolamine and (-)-1-epi-valiolamine from (-)-vibo-quercitol

The synthesis of (+)-valiolamine and (-)-1-epi-valiolamine using bioconversion of (-)-vibo-quercitol was investigated. The quercitols were separated and purified by combination of chromatography on ion-exchange-resin columns and recrystallization. Valiolamine was isolated from fermentation broth of antibiotic validamycins. The obtained crude ketone was subjected to C-C bond formation conditions in which diazomethane was considered adequate in polar and protic solvsnts.

Synthesis of polyhydroxycyclohexanes and relatives from (-)-quinic acid

An efficient and versatile strategy for the synthesis of polyhydroxycyclohexanes and related compounds 3-6 is reported. The successful synthesis of these analogues has been achieved from a common intermediate, quinic acid derived lactone 2, rapidly access