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2-(chloromethyl)-1-(difluoromethyl)-1H-benzimidazole hydrochloride is a pharmaceutically significant benzimidazole derivative characterized by the presence of a chloromethyl and a difluoromethyl group. It is typically found in the form of a hydrochloride salt and is known for its diverse biological activities, including antimicrobial and antifungal properties, making it a valuable component in the development of drugs and therapeutic agents.

1153151-54-2

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1153151-54-2 Usage

Uses

Used in Pharmaceutical Research and Development:
2-(chloromethyl)-1-(difluoromethyl)-1H-benzimidazole hydrochloride is used as a key intermediate in the synthesis of various drugs and therapeutic agents. Its unique chemical structure allows for the development of compounds with specific biological activities, contributing to the advancement of novel treatments for various diseases.
Used in Antimicrobial and Antifungal Agents:
In the pharmaceutical industry, 2-(chloromethyl)-1-(difluoromethyl)-1H-benzimidazole hydrochloride is utilized as an antimicrobial and antifungal agent. Its inherent properties enable the creation of medications that combat a wide range of microbial infections, providing effective treatment options for patients suffering from bacterial and fungal diseases.
Used in Drug Synthesis:
2-(chloromethyl)-1-(difluoromethyl)-1H-benzimidazole hydrochloride serves as a crucial building block in the synthesis of pharmaceutical compounds. Its versatile chemical structure allows for the development of drugs with targeted therapeutic effects, enhancing the efficacy and safety of treatments for various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1153151-54-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,3,1,5 and 1 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1153151-54:
(9*1)+(8*1)+(7*5)+(6*3)+(5*1)+(4*5)+(3*1)+(2*5)+(1*4)=112
112 % 10 = 2
So 1153151-54-2 is a valid CAS Registry Number.

1153151-54-2Downstream Products

1153151-54-2Relevant academic research and scientific papers

Multigram synthesis of 1-(difluoromethyl)imidazoles and -benzimidazoles

Levterov, Vadym,Grygorenko, Oleksandr O.,Mykhailiuk, Pavel K.,Tolmachev, Andrey A.

experimental part, p. 1243 - 1248 (2011/05/14)

An expedient approach to the difluoromethylation of imidazoles and benzimidazoles has been developed. The key feature of the procedure is the gradual generation of the difluoromethylation reagent in the reaction mixture, which is achieved by the simultane

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