1153474-59-9Relevant academic research and scientific papers
Concise access to enantiopure (S)- and (R)-α-trifluoromethyl pyroglutamic acids from ethyl trifluoropyruvate-based chiral CF3-oxazolidines (Fox)
Chaume, Grégory,Van Severen, Marie-Céline,Ricard, Louis,Brigaud, Thierry
, p. 1104 - 1109 (2008)
A straightforward synthesis of enantiopure (S)- and (R)-α-Tfm-pyroglutamic acid is reported. The strategy is based on the use of a chiral CF3-hydroxymorpholinone intermediate conveniently obtained from ethyl trifluoropyruvate-based chiral CFsu
