1153631-91-4

Upstream product

• 1067222-49-4 ethyl 4-[(4-methoxyphenyl)amino]-6-(methylcarbamoyl)quinoline-3-carboxylate 

Downstream Products

• 1153631-93-6 butyl 4-[(4-methoxyphenyl)amino]-6-(methylcarbamoyl)quinoline-3-carboxylate 
• 1153631-95-8 methyl 4-[(4-methoxyphenyl)amino]-6-(methylcarbamoyl)quinoline-3-carboxylate 
• 1256485-20-7 (methoxycarbonyl(methyl)amino)methyl 4-(4-methoxyphenyl-amino)-6-(methylcarbamoyl)-quinoline-3-carboxylate 
• 1256485-27-4 (2-methoxy-1-methyl-2-oxo-ethyl)4-[(4-methoxyphenyl)-amino]-6-(methylcarbamoyl)quinoline-3-carboxylate 
• 1256485-29-6 acetoxymethyl 4-[(4-methoxy-phenyl)amino]-6-(methyl-carbamoyl)quinoline-3-carboxylate 
• 1256485-25-2 2-(dimethylamino)-2-oxoethyl-4-(4-methoxyphenyl-amino)-6-(methyl-carbamoyl)quinoline-3-carboxylate 
• 1256485-23-0 2-(dimethylamino)-ethyl4-(4-methoxyphenyl-amino)-6-(methylcarbamoyl)-quinoline-3-carboxylate 
• 1256485-34-3 2-imidazol-1-ylethyl 4-[(4-methoxyphenyl)-amino]-6-(methylcarbamoyl)-quinoline-3-carboxylate 
• 1256485-36-5 2-morpholinoethyl 4-[(4-methoxyphenyl)amino]-6-(methylcarbamoyl)-quinoiine-3-carboxylate 
• 1256485-18-3 (1H-imidazol-1-yl)methyl 4-(4-methoxyphenylamino)-6-(methylcarbamoyl)-quinoline-3-carboxylate 
• 1256485-38-7 (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-[(4-methoxyphenyl)amino]-6-(methylcarbamoyl)quinoline-3-carboxylate 
• 1256485-22-9 (N-methylbenzamido)methyl 4-(4-methoxyphenyl-amino)-6-(methyl-carbamoyl)-quinoline-3-carboxylate 
• 1256485-30-9 (methylsulfonyl(phenyl)amino)methyl 4-[(4-methoxyphenyl)-amino]-6-(methylcarbamoyl)-quinoline-3-carboxylate 

Relevant academic research and scientific papers

SUBSTITUTED QUINOLINES FOR USE AS VEGF INHIBITORS

A compound of formula (I), as well as pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising a therapeutically effective amount of the compounds. The compound is useful in treatment of cancer, diabetic retinopathy, age-related macular degeneration, inflammation, stroke, ischemic myocardium, atherosclerosis, macular edema and psoriasis.

COMPOUNDS AND METHODS

A compound of formula (I) as well as pharmaceutically acceptable salts thereof. A pharmaceutical composition comprising a therapeutically effective amount of the compound. The compound is useful for the treatment of cancer, diabetic retinopathy, age-relat