115369-27-2

Upstream product

• 115369-26-1 (R)-4-Benzenesulfonyl-1-benzyloxy-butan-2-ol 
• 81582-94-7 4-(-phenylsulfonyl)-1,2-epoxybutane 
• 115369-25-0 (R)-1-Benzyloxy-4-phenylsulfanyl-butan-2-ol 
• 108-98-5 thiophenol 
• 67100-44-1 (but-3-en-1-ylsulfonyl)benzene 
• 873-55-2 sodium benzenesulfonate 

Downstream Products

• 363625-07-4 Butyric acid (R)-3-benzenesulfonyl-1-butyryloxymethyl-propyl ester 
• 1422044-17-4 C₂₂H₃₀O₆S 
• 1422044-20-9 C₁₉H₂₅N₃O₅S 
• 1422044-12-9 C₁₃H₁₈O₄S 
• 1422044-22-1 C₃₄H₅₉N₃O₅SSi₂ 
• 1422044-21-0 C₁₉H₂₄O₅S 
• 1422044-19-6 C₂₈H₃₆O₈S₂ 
• 1422044-18-5 C₁₉H₂₆O₆S 
• 1422044-24-3 C₂₈H₄₅NO₄SSi 
• 1422044-23-2 C₃₄H₅₉NO₄SSi₂ 
• 115369-31-8 (R)-4-Benzenesulfonyl-1-((4aR,6R,7R,8S,8aR)-7-benzyloxy-8-methoxymethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-7-(tert-butyl-diphenyl-silanyloxy)-6-(1-ethoxy-ethoxy)-heptan-3-one 
• 115369-30-7 (R)-4-Benzenesulfonyl-1-((4aR,6R,7R,8S,8aR)-7-benzyloxy-8-methoxymethoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-7-(tert-butyl-diphenyl-silanyloxy)-6-(1-ethoxy-ethoxy)-heptan-3-ol 
• 115369-29-4 [(R)-4-Benzenesulfonyl-2-(1-ethoxy-ethoxy)-butoxy]-tert-butyl-diphenyl-silane 
• 363625-13-2 butyric acid 4-benzenesulfonyl-2-(tert-butyl-dimethyl-silanyloxy)-butyl ester 

Relevant academic research and scientific papers

Unified Synthesis of 10-Oxygenated Lycopodium Alkaloids: Impact of C10-Stereochemistry on Reactivity

The pronounced impact of the C10 stereochemistry on the successful construction of a polycyclic Lycopodium alkaloid scaffold has been explored. A wide range of reaction conditions and functionality were investigated to control a keto sulfone Michael addition to construct the C7-C12 linkage. An unexpected, overriding impact of the C10 stereochemistry in stereoselectivity and reaction rate in the Michael addition was observed. Furthermore, divergent reactivity of a conformationally accelerated, intramolecular Mannich cyclization based on the C10 stereochemistry was discovered. The successful execution of this synthetic route resulted in the total synthesis of all three known 10-oxygenated Lycopodium alkaloids: 10-hydroxylycopodine, paniculine, and deacetylpaniculine.

Diastereoselective synthesis of tetrahydrofurans via reaction of γ,δ-epoxycarbanions with aldehydes

(Chemical Equation Presented) Hydroxymethyl-substituted tetrahydrofurans were prepared with high diastereoselectivity by reaction of the carbanion derived from 3,4-epoxybutyl phenyl sulfone with aldehydes in the presence of a mixture of lithium and potass

Chiral non-racemic dihydroxysulfones via hydrolytic kinetic resolutions - Synthesis of oxacyclic ring systems using intramolecular acylation strategies

A number of chiral non-racemic 1,2-dihydroxysulfones have been prepared in good yields and high enantiomeric excesses by hydrolytic kinetic resolution of the corresponding epoxysulfones with Jacobsen's (S,S)-salen(Co)III(OAc) catalyst. The intramolecular cyclization reactions of the acyl and ethoxycarbonyl derivatives of these dihydroxysulfones have been exploited to access a variety of functionalized chiral non-racemic cyclic ethers and lactones in good yields.

SYNTHESIS OF A MARINE POLYETHER TOXIN, OKADAIC ACID (2) -- SYNTHESIS OF SEGMENT B

The central synthetic segment B for okadaic acid comprises the carbons from 15 through 27 including 6 asymmetric carbons.Its synthesis started from a D-glucose derivative, whose carbon was extended twice for the six and five membered etherial ring formati