115376-70-0Relevant articles and documents
Synthesis of 3-Hydroxy-2,6-dimethyl-1-phenyl- and 3,4-Dihydroxy-2,6-dimethyl-1-phenyl-acetic Acids, Two Potential Synthons
Raju, B.,Rao, G. S. Krishna
, p. 469 - 470 (2007/10/02)
4-t-Butyl-3-hydroxy-2,6-dimethyl-1-benzylchloride (VIII), obtained from 2,4-dimethylphenol (VI), is converted into the cyanomethylphenols (IX) or (X) depending on the experimental conditions and both give the phenylacetic acid (I).Compound I in turn affords the dihydroxyphenylacetic acid (XII), via the 1,2-benzoquinone (XIII), by iodoxybenzene oxidation, reductive acetylation and hydrolysis.