115377-39-4

Upstream product

• 603-35-0 triphenylphosphine 
• 65117-56-8 ethyl (2Z,4E)-2-azido-5-phenylpenta-2,4-dienoate 

Downstream Products

• 115377-42-9 (2Z,4E)-2-(4-Methoxy-phenyliminomethyleneamino)-5-phenyl-penta-2,4-dienoic acid ethyl ester 
• 115377-49-6 ethyl 6-(4-methoxyphenylamino)-5-phenyl-2-pyridinecarboxylate 
• 115377-46-3 (2Z,4E)-2-tert-Butyliminomethyleneamino-5-phenyl-penta-2,4-dienoic acid ethyl ester 
• 115377-53-2 ethyl 6-(tert-butylamino)-5-phenyl-2-pyridinecarboxylate 
• 115377-45-2 (2Z,4E)-2-Ethyliminomethyleneamino-5-phenyl-penta-2,4-dienoic acid ethyl ester 
• 115377-52-1 ethyl 6--5-phenyl-2-pyridinecarboxylate 
• 115377-50-9 ethyl 6-(4-bromophenylamino)-5-phenyl-2-pyridinecarboxylate 
• 115377-43-0 (2Z,4E)-2-(4-Bromo-phenyliminomethyleneamino)-5-phenyl-penta-2,4-dienoic acid ethyl ester 
• 115377-41-8 (2Z,4E)-5-Phenyl-2-p-tolyliminomethyleneamino-penta-2,4-dienoic acid ethyl ester 
• 115377-48-5 ethyl 6-(4-methylphenylamino)-5-phenyl-2-pyridinecarboxylate 
• 115377-47-4 ethyl 5-phenyl-6-(phenylamino)-2-pyridinecarboxylate 
• 115377-40-7 (2Z,4E)-5-Phenyl-2-phenyliminomethyleneamino-penta-2,4-dienoic acid ethyl ester 
• 115377-44-1 (2Z,4E)-2-(4-Chloro-phenyliminomethyleneamino)-5-phenyl-penta-2,4-dienoic acid ethyl ester 
• 115377-54-3 (2Z,4E)-2-Isothiocyanato-5-phenyl-penta-2,4-dienoic acid ethyl ester 

Relevant academic research and scientific papers

Reactivity and Selectivity of N-Vinylic λ5-Phosphazenes towards Electrophiles. Synthesis of 2-Aza-1,3-dienes

The reactivity of the P=N double bond of the N-vinylic λ5-phosphazene (1) towards several electrophiles is reported.Intermolecular aza-Wittig reaction of λ5-phosphazene (1) with aldehydes, phenyl isocyanate, and acid anhydrides leads to ethoxycarbonyl 2-aza-1,3-dienes (3), conjugated carbodi-imides (4), and N-protected amino acrylic acid derivatives (5), respectively, while the 2-azahexa-1,3,5-triene (8) and also the pyridine (7) are obtained when dienyl λ5-phosphazenes (6) are used.Reaction of λ5-phosphazene (1) with methyl iodide and acetyl chloride leads to N-alkylated (10) and N-acylated derivatives (11), respectively.Treatment of compound (11) in the presence of amino derivatives affords 1-amino-2-azabuta-1,3-dienes (14).

Heterocyclization Reactions of Conjugated Heterocumulenes. Synthesis of Pyridine Derivatives by a Tandem Aza Wittig/Electrocyclization Strategy

The aza Wittig reaction of iminophosphorane 3 with isocyanates leads to conjugated carbodiimides 4, which undergo electrocyclic ring closure to give ethyl 2-pyridinecarboxylates 5.Iminophosphorane 9 reacts with nitromethane and acetone in a 1:1 molar rati

CONJUGATED CARBODIIMIDES: PREPARATION AND THERMAL CYCLIZATION TO 2-AMINOPYRIDINE DERIVATIVES

The aza-Wittig reaction of iminophosphorane (2) with isocyanates leads to conjugated carbodiimides which undergo electrocyclic ring-closure to give 2-aminopyridine derivatives.