115395-69-2Relevant academic research and scientific papers
Two-step phosphorus-mediated substitution of hydroxy groups in selected primary alcohols for fluorinated alkyl or aryl substituents: The molecular structure of 1,1-bis(fluorosulfonyl)-1-fluoro-2-phenylethane
Kolomeitsev, Alexander,Shtarev, Alexander,Chabanenko, Kyrill,Savina, Tatjana,Yagupolskii, Yurii,Goerg, Michaela,Przyborowski, Jan,Lork, Enno,Roeschenthaler, Gerd-Volker
, p. 705 - 706 (2007/10/03)
In an Arbuzov type reaction, amido phosphites (Et2N)2-POR1 and a broad range of halofluoro organic halides (X = Cl, Br) formed the corresponding alkylated derivatives R1-R2 [R1 = Bn, R
Advances in trifluoromethylating phosphorus compounds
Kolomeitsev, Alexander,Goerg, Michaela,Dieckbreder, Uwe,Lork, Enno,Roeschenthaler, Gerd-Volker
, p. 597 - 600 (2007/10/03)
The System CF3IMe3P is re-investigated and Me2PCF3, Me4P+I-, (CF3)2PMe3, Me3PI2, [Me3(CF3)P]+I- are found as products. Using CF3Br/P(NEt2)3 the phosphines R12PCF3 and R1P(CF3)2 (e.g. R1 = Me, iPr, NEt2) can be obtained which are precursors either for phosphoranes (e.g. 1,2λ5σ5-oxaphosphetanes) or phosphonium salts (e.g. [R12(Me)PCF3]+X- or [R1(Me)P(CF3)2X-]. The latter are deprotonated to furnish methylene phosphoranes R12(CH2=)PCF3 or R1(CH2=)P(CF3)2, reactive synthons. From CF3Br/ P(NEt2)3/P(OPh)3 the phosphine P(CF3)3 is available, which turned out to be a potent electrophile. Amido phospites ROP(NEt2)2 and halides R2X (R2= CCl2CF3, X= Cl; R2= CF=CFCF3, X= F; R2= C6F5, X= Br, I; R2= C(CF3)3, X= Br; R2= SCF3, X= CF3) undergo an ARBUZOV reaction.
