115398-02-2

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 3959-05-5 2-bromobenzylamine 

Downstream Products

• 1337882-80-0 [PtBr(2-CH₃C₆H₃C₆H₄CH=NCH₂(2-C₆H₄Br))SEt₂] 

Relevant academic research and scientific papers

Switch in Catalyst State: Single Bifunctional Bi-state Catalyst for Two Different Reactions

Disclosed here is a molecular switch which responds to acid-base stimuli and serves as a bi-state catalyst for two different reactions. The two states of the switch serve as a highly active and poorly active catalyst for two catalytic reactions (namely a hydrogenation and a dehydrogenative coupling) but in a complementary manner. The system was used in an assisted tandem catalysis set-up involving dehydrogenative coupling of an amine and then hydrogenation of the resulting imine product by switching between the respective states of the catalyst.

Zinc porphyrin-based electron donor–acceptor-conjugated microporous polymer for the efficient photocatalytic oxidative coupling of amines under visible light

The application of porous organic polymers is an emerging area of heterogeneous photocatalytic organic synthesis. In principle, the transfer of energy and electrons is significant to improve the photocatalytic efficiency. To obtain an efficient energy- an

Robust porous organic polymers as efficient heterogeneous organo-photocatalysts for aerobic oxidation reactions

Metal-free, visible-light active and heterogeneous organic photocatalysts offer a more sustainable and environmentally friendly alternative to traditional metal-based catalysts. Here a porous organic hyper-crosslinked polymer, CF-HCP, was successfully syn

2,4,6-Trihydroxybenzoic Acid-Catalyzed Oxidative Ugi Reactions with Molecular Oxygen via Homo- And Cross-Coupling of Amines

Metal-free, oxidative four-component Ugi reactions (U-4CRs) were conducted to synthesize dipeptides from two different amines, isocyanides, and carboxylic acids using 2,4,6-trihydroxybenzoic acid catalyst in O2 atmosphere. The organocatalytic U-4CRs proceed via oxidative cross-coupling of benzylamines with other aliphatic or aromatic amines to form imines, followed by condensation with isocyanides and carboxylic acids. The U-4CRs via cross-coupling of amines are rare, and the simple, metal-free procedures are advantageous for further applications in drug and heterocycle syntheses.

Covalent-organic frameworks with keto-enol tautomerism for efficient photocatalytic oxidative coupling of amines to imines under visible light

Photocatalytic oxidation of organic molecules into highly value-added products is an innovative and challenging research which has gradually attracted remarkable attention of scientists. In this work, it is demonstrated that the COF-TpPa with keto-enol ta

An anthracene extended viologen-incorporated ionic porous organic polymer for efficient aerobic photocatalysis and antibacterial activity

A new conjugated ionic porous organic polymer (AN-POP), incorporated with anthracene-extended viologen, has been rationally designed and prepared to explore its dual functions in photocatalytic oxidation and bacterial killing. Compared with its anthracene

β-Diketone boron difluoride dye-functionalized conjugated microporous polymers for efficient aerobic oxidative photocatalysis

Incorporation of organic chromophores into conjugated micro/mesoporous polymers (CMPs) provides a promising avenue for developing recyclable heterogeneous photocatalysts by overcoming tedious separation and low reusability of homogeneous organic dye-based photocatalysts. However, the design principle and the underlying structure-property relationship for fabricating and selecting various organic dye-embedded CMPs for efficient photocatalysis have not been well-constructed so far. In this study, we described the rational fabrication of two new CMPsviathe one-step Sonogashira coupling using β-diketone boron difluoride dye as the key linker and commonly used building blocks (triphenylamine/triphenylbenzene) as the cores. The resulting boron-dye containing CMPs were efficiently employed as the metal-free photocatalysts in two typical aerobic oxidative organic transformations including coupling of benzylamine and oxidation of aryl boronic acids to corresponding aryl phenols, which have never been explored with other boron-dye-embedded CMPs. They exhibited superior photocatalytic performance compared to their boron-free counterparts due to their wide visible-light absorption, narrow optical bandgaps, and extended π-conjugation due to boron-complexation. The present study establishes β-diketone boron difluoride dyes as efficient building blocks for fabricating new CMP-based photocatalysts.

Au/TiO2nanobelts: Thermal enhancement: Vs. plasmon enhancement for visible-light-driven photocatalytic selective oxidation of amines into imines

Thermo-enhanced photocatalysis has been reported as a potential strategy for improving the activity, whereas the relationship between thermal energy and the localized surface plasmon resonance (LSPR) effect of noble metal nanoparticles has been rarely investigated. Herein, photocatalytic selective aerobic oxidation of amines to imines is investigated under visible light irradiation over heterostructured TiO2(B)/anatase and Au/TiO2 nanobelts at specific temperatures (20-60 °C). The surface amine substrate complexed on TiO2 could broaden the visible-light absorption region via the ligand-to-metal charge transfer (LMCT) effect. Interestingly, the pristine TiO2 achieves the best photocatalytic performance (>99% benzylamine conversion and >99% N-benzylidenebenzylamine selectivity) at 60 °C after 12 h irradiation while the Au nanoparticles (NPs) are observed to improve the activity of TiO2 only in a low temperature range (A plausible explanation is finally proposed that the substrate-TiO2 complex, instead of plasmonic Au NPs, plays a vital role in achieving good amine conversion and imine selectivity. This journal is

Reusable Nickel Nanoparticles-Catalyzed Reductive Amination for Selective Synthesis of Primary Amines

The preparation of nickel nanoparticles as efficient reductive amination catalysts by pyrolysis of in situ generated Ni-tartaric acid complex on silica is presented. The resulting stable and reusable Ni-nanocatalyst enables the synthesis of functionalized and structurally diverse primary benzylic, heterocyclic and aliphatic amines starting from inexpensive and readily available carbonyl compounds and ammonia in presence of molecular hydrogen. Applying this Ni-based amination protocol, -NH2 moiety can be introduced in structurally complex compounds, for example, steroid derivatives and pharmaceuticals.

Selectivity-tunable amine aerobic oxidation catalysed by metal-free N,O-doped carbons

Herein, we present a series of N,O-doped mesoporous carbons obtained at different pyrolysis temperatures as the first metal-free catalysts which successfully switch between imine and nitrile products for amine oxidation. Systematic characterization studies and control experiments revealed that the C-O group on the surface could function as a catalytically active site for nitrile synthesis and the N-doping environment was essential.