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5-(N-butyl-N-methyl)amiloride, also known as 5-N-butyl-N-methylamiloride or 5-N-BMA, is a chemical compound that functions as a potent and selective inhibitor of the epithelial sodium channel (ENaC). ENaC is a protein found in the cell membranes of various tissues, including the lungs, kidneys, and colon, and plays a crucial role in regulating sodium ion transport across cell membranes. By inhibiting ENaC, 5-N-BMA can reduce sodium absorption, which in turn can lower blood pressure and alleviate edema in certain conditions. 5-(N-butyl-N-methyl)amiloride is structurally similar to amiloride, a well-known ENaC inhibitor, but with a butyl group replacing the ethyl group in amiloride, enhancing its potency and selectivity. 5-N-BMA is primarily used in scientific research to study the role of ENaC in various physiological and pathological processes, and its potential therapeutic applications in conditions such as hypertension and heart failure are also being explored.

1154-79-6

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1154-79-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1154-79-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,5 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1154-79:
(6*1)+(5*1)+(4*5)+(3*4)+(2*7)+(1*9)=66
66 % 10 = 6
So 1154-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H18ClN7O/c1-3-4-5-19(2)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h3-5H2,1-2H3,(H2,13,17)(H4,14,15,18,20)

1154-79-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-5-[butyl(methyl)amino]-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide

1.2 Other means of identification

Product number -
Other names N5-Butyl-N5-methylamiloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1154-79-6 SDS

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