115400-41-4

Upstream product

• 141-43-5 ethanolamine 
• 66537-92-6 methyl 2,3-anhydro-4,6-benzylidene-α-D-allopyranoside 

Downstream Products

• 126999-29-9 (2R,4aR,6S,6aS,22aS,22bS)-6-Methoxy-2-phenyl-hexadecahydro-1,3,5,10,13,16,19,22-octaoxa-7-aza-cyclooctadeca[a]naphthalene 
• 126946-42-7 (1S,15S,16S,18R,21R,23S)-23-Methoxy-18-phenyl-5,8,11,14,17,19,22-heptaoxa-2-aza-tricyclo[13.8.0.0^16,21]tricosane 
• 231607-30-0 methyl 4,6-O-benzylidene-2-<2-(4-<4-phenyl>butanoyloxy)ethylamino>-2-deoxy-α-D-altropyranoside 
• 126999-30-2 (1S,15S,16S,18R,21R,23S)-2-Ethyl-23-methoxy-18-phenyl-5,8,11,14,17,19,22-heptaoxa-2-aza-tricyclo[13.8.0.0^16,21]tricosane 
• 126946-43-8 (2R,4aR,6S,7S,8S,8aS)-7-[Ethyl-(2-hydroxy-ethyl)-amino]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-ol 

Relevant academic research and scientific papers

A general method for synthesis of alkyl 2-N-substituted and 2-N,N-disubstituted D-altrosamines

Keywords: Amino sugar; 2-N-alkyl-D-altrosamines

Alkylating agents from sugars. Alkyl hexopyranoside derivatives as carrier systems for chlorambucil

Chlorambucil derivatives involving alkyl 2-aminodeoxy sugars have been synthesized in good yield by coupling the chlorambucil moiety to positions C-2 or C-3 of the sugar, directly or via a spacer. The starting material was easily available from 2-acetamido-2-deoxy-D-glucose. The final compounds were tested for cytotoxicity, and some of those that presented the best results were studied for inhibition of cell proliferation. Copyright (C) 1999 Elsevier Science Ltd.