1154060-75-9

Upstream product

• 6311-35-9 6-bromonicotinic acid 
• 27291-96-9 benzene-1,2-disulfonamide 

Downstream Products

• 1154059-77-4 6-(Cyclopentylethynyl)-N-(2-sulfamoylphenylsulfonyl)nicotinamide 
• 1255706-95-6 N-(2-sulfamoylphenylsulfonyl)-6-((4-(trifluoromethyl)phenyl)ethynyl)nicotinamide 

Relevant academic research and scientific papers

BIS-(SULFONYLAMINO) DERIVATIVES FOR TREATMENT OF PAIN AND INFLAMMATION

The invention provides compounds of formula (I) wherein R1, R2, R3, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together

BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065

The invention provides compounds of formula wherein R1, R2, R3, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1

BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066

The invention provides compounds of formula wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.