115419-53-9

Upstream product

• 115419-51-7 3-phenyl-propionic acid-(N'-phenyl-hydrazide) 
• 70794-15-9 3-phenylpropionaldehyde phenylhydrazone 
• 104-53-0 3-phenyl-propionaldehyde 
• 122-97-4 3-Phenyl-1-propanol 

Relevant academic research and scientific papers

Facile One-Pot Transformation of Primary Alcohols into 3-Aryl- and 3-Alkyl-isoxazoles and -pyrazoles

Various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylisoxazoles in good yields in one pot by successive treatment with PhI(OAc) 2 in the presence of TEMPO, NH 2 OH, and then NCS, followed by reaction with alkynes in the presence of Et 3 N. Similarly, various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylpyrazoles in good yields in one pot by successive treatment with PhI(OAc) 2 in the presence of TEMPO, PhNHNH 2, and then NCS and decyl methyl sulfide, followed by reaction with alkynes in the presence of Et 3 N. Thus, both 3-aryl- and 3-alkylisoxazoles, and 3-aryl- and 3-alkylpyrazoles could be prepared from readily available primary alcohols in one pot under transition-metal-free conditions.

Synthesis of N-Phenylalkanehydrazonoyl Chlorides

N-Phenylalkanehydrazonoyl chlorides (5), hitherto unknown, were synthesized from the corresponding arylhydrazides of aliphatic carboxylic acids (1) with triphenylphosphine-carbon tetrachloride in good yields.Keywords-N-phenylalkanehydrazonoyl chloride; ar