115441-64-0Relevant academic research and scientific papers
Synthesis of [Gly-1]RA-VII, [Gly-2]RA-VII, and [Gly-4]RA-VII. Glycine-Containing Analogues of RA-VII, an Antitumor Bicyclic Hexapeptide from Rubia Plants
Hitotsuyanagi, Yukio,Hasuda, Tomoyo,Aihara, Takayuki,Ishikawa, Hiroshi,Yamaguchi, Kentaro,Itokawa, Hideji,Takeya, Koichi
, p. 1481 - 1486 (2007/10/03)
Three analogues of RA-VII (1), an antitumor bicyclic hexapeptide from Rubia plants, were synthesized. Three analogues, [Gly-1]RA-VII (4), [Gly-2]RA-VII (5), and [Gly-4]RA-VII (6), in which one of the three alanine residues in 1 was replaced by a glycine r
Isolation, structural elucidation, and synthesis of RA-XVII, a novel bicyclic hexapeptide from Rubia cordifolia, and the effect of side chain at residue 1 upon the conformation and cytotoxic activity
Hitotsuyanagi, Yukio,Ishikawa, Hiroshi,Hasuda, Tomoyo,Takeya, Koichi
, p. 935 - 938 (2007/10/03)
A novel antitumor bicyclic hexapeptide RA-XVII was isolated from the roots of Rubia cordifolia. By spectral studies and synthetic approach, its structure was determined to be [D-2-aminobutyric acid-1]deoxybouvardin. Studies on the effect of side chain at
Regioselective synthesis of 14-membered biaryl ethers: Total synthesis of RA-VII and deoxybouvardin
Inoue,Inaba,Umezawa,Yuasa,Itokawa,Ogura,Komatsu,Hara,Hoshino
, p. 1325 - 1335 (2007/10/02)
In order to obtain a key compound (22a'') for synthesis of RA-VII (1) and deoxybouvardin (2), construction of the 14-membered ring system was performed by means of thallium trinitrate-mediated oxidation of the tetrahalogeno amides 5-7. The dibromo dichlor
