1154422-01-1

Basic information

• Product Name: 3-hydroxy-1-(3-hydroxyphenyl)-2-methylpyridin-4(1H)-one
• CAS NO: 1154422-01-1
• Molecular Weight: 217.224
• Mol File: 1154422-01-1.mol

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-1-(3-hydroxyphenyl)-2-methylpyridin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-1-(3-hydroxyphenyl)-2-methylpyridin-4(1H)-one(1154422-01-1)
• EPA Substance Registry System: 3-hydroxy-1-(3-hydroxyphenyl)-2-methylpyridin-4(1H)-one(1154422-01-1)

Safety Data

• Hazardous Substances Data: 1154422-01-1(Hazardous Substances Data)

Upstream product

• 118-71-8 Maltol 
• 591-27-5 m-Hydroxyaniline 

Relevant articles and documents

Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives

A series of Mannich bases of 2-alkyl-3-hydroxy-pyridine-4-ones, namely 2-alkyl-3-hydroxy-5-N-piperidylmethyl or N,N-dialkylaminomethyl pyridine-4-ones 9, 10 and 15-18, two derivatives of N-aryl-2-methyl-3-hydroxy-pyridine-4-ones 19, 20 and two N-alkyl derivatives of maltol, 21 and 22 were prepared. They were screened for their antibacterial and antifungal activities against a variety of microorganisms using micro plate Alamar Blue assay (MABA) method. Multiple linear regressions (MLR) analysis was performed for the synthesized compounds as well as a series of pyridinone and pyranone derivatives 23-43 which have been synthesized and evaluated for antimicrobial activity by other researchers previously. Studied compounds showed a better quantitative structure-activity relationship (QSAR) model for the antimicrobial activity against Candida albicans and Staphylococcus aureus in comparison with other tested microorganisms.