115461-13-7Relevant academic research and scientific papers
Felkin-Anh-Selective Hiyama Addition to O-Protected Lactaldehydes: A General Solution to the Blastmycinone Stereoproblem.
Mulzer, Johann,Schulze, Thomas,Strecker, Achim,Denzer, Wolfgang
, p. 4098 - 4103 (2011/08/10)
The Hiyama addition of 6a-c to the O-protected lactaldehydes 5a,b, proceeds with high Felkin-Anh selectivity. 7c, readily available in 20-g quantities, is the key intermediate in diastereocontrolled syntheses of all blastmycinolactol diastereomers (1-4a) in enantiomerically pure form.
