115464-87-4

Basic information

• Product Name: 1H-Pyrrole, 2,2'-methylenebis[5-phenyl-
• CAS NO: 115464-87-4
• Molecular Formula: C21H18N2
• Molecular Weight: 298.387
• Mol File: 115464-87-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 2,2'-methylenebis[5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 2,2'-methylenebis[5-phenyl-(115464-87-4)
• EPA Substance Registry System: 1H-Pyrrole, 2,2'-methylenebis[5-phenyl-(115464-87-4)

Safety Data

• Hazardous Substances Data: 115464-87-4(Hazardous Substances Data)

Upstream product

• 3042-22-6 2-phenyl-1H-pyrrole 
• 50-00-0 formaldehyd 
• 35386-24-4 1-(2-Methoxyphenyl)piperazine 

Relevant articles and documents

2-Phenylpyrroles as Conformationally Restricted Benzamide Analogues. A New Class of Potential Antipsychotics. 2

A series of 2-phenylpyrrole Mannich bases was synthesized and screened in pharmacological models for antipsychotic activity and extrapyramidal effects.Structure modifications of 5-(4-fluorophenyl)-2-methyl>pyrrole (1), the prototype of a new class of sodium-independent atypical dopamine D-2 antagonists, resulted in 2-methyl>-5-(4-fluorophenyl)pyrrole (15), which was an even more potent and selective D-2 antagonist than the parent compound.The excellent oral activity in the apomorphine-induced climbing behavior and the conditioned avoidance response tests and the absence of catalepsy make this compound particularly promising as a potential antipsychotic with a low propensity to induce acute extrapyramidal side effects.