115473-51-3 Usage
General Description
L-Glutamic-3-13C acid is a stable isotope of glutamic acid, in which carbon-13 is substituted for some of the naturally occurring carbon-12 atoms. It is a non-essential amino acid that plays a key role in the metabolism of protein and the regulation of neurotransmitters. L-Glutamic-3-13C acid is commonly used in metabolic labeling studies to track the flow of carbon atoms through biochemical pathways. It is also used in nuclear magnetic resonance (NMR) spectroscopy to study the structure and dynamics of proteins and other biomolecules. Additionally, L-Glutamic-3-13C acid has potential applications in medical research and pharmaceutical development, particularly in the study of metabolic diseases and the design of novel drug therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 115473-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,4,7 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115473-51:
(8*1)+(7*1)+(6*5)+(5*4)+(4*7)+(3*3)+(2*5)+(1*1)=113
113 % 10 = 3
So 115473-51-3 is a valid CAS Registry Number.
115473-51-3Relevant articles and documents
Chemo-enzymatic synthesis of specifically stable-isotope labelled L-glutamic acid and 2-oxoglutaric acid
Cappon, J. J.,Baart, J.,Walle, G. A. M. van der,Raap, J.,Lugtenburg, J.
, p. 158 - 166 (2007/10/02)
(3-13C)-(4-13C)-,(5-13C)- and (3,4-13C2)-2-oxoglutaric acid were prepared starting from the simple 13C-enriched compounds: ethyl bromoacetate and paraformaldehyde, via a single reaction scheme on the gram scale in high yield.This reaction scheme allows specific 13C enrichment of every carbon position and any combination of positions. (3-13C)-,(4-13C)-, (5-13C), (3,4-13C2) and (15N)-L-glutamic acid were prepared by converting the corresponding 2-oxoglutaric acids via an enantioselective enzymatic conversion.The labelled L-glutamic acids and 2-oxoglutaric acids were characterized by 1H NMR, 13C NMR and mass spectrometry.
