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L-Glutamic-3-13C acid is a stable isotope of glutamic acid, in which carbon-13 is substituted for some of the naturally occurring carbon-12 atoms. It is a non-essential amino acid that plays a key role in the metabolism of protein and the regulation of neurotransmitters.
Used in Metabolic Labeling Studies:
L-Glutamic-3-13C acid is used as a metabolic tracer for tracking the flow of carbon atoms through biochemical pathways. This application is crucial for understanding metabolic processes and identifying metabolic pathways involved in various biological functions and diseases.
Used in Nuclear Magnetic Resonance (NMR) Spectroscopy:
L-Glutamic-3-13C acid is used as a structural probe in NMR spectroscopy to study the structure and dynamics of proteins and other biomolecules. The incorporation of carbon-13 allows for enhanced resolution and sensitivity in NMR experiments, providing detailed insights into molecular interactions and conformational changes.
Used in Medical Research and Pharmaceutical Development:
L-Glutamic-3-13C acid is used as a research tool in the study of metabolic diseases, enabling the investigation of altered metabolic pathways and the identification of potential therapeutic targets. Additionally, it has potential applications in the design of novel drug therapies, where its unique isotopic properties can be leveraged to monitor drug metabolism and efficacy.
Used in Neurotransmitter Regulation Studies:
L-Glutamic-3-13C acid is used as a neurotransmitter modulator, aiding in the study of its role in the regulation of neurotransmitter release and function. This application is important for understanding the mechanisms underlying neurological disorders and developing treatments targeting neurotransmitter imbalances.

115473-51-3

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115473-51-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 115473-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,4,7 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115473-51:
(8*1)+(7*1)+(6*5)+(5*4)+(4*7)+(3*3)+(2*5)+(1*1)=113
113 % 10 = 3
So 115473-51-3 is a valid CAS Registry Number.

115473-51-3 Well-known Company Product Price

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  • Aldrich

  • (490016)  L-Glutamic acid-3-13C  99 atom % 13C

  • 115473-51-3

  • 490016-100MG

  • 14,437.80CNY

  • Detail

115473-51-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name L-Glutamic acid-3-13C

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:115473-51-3 SDS

115473-51-3Downstream Products

115473-51-3Relevant academic research and scientific papers

Chemo-enzymatic synthesis of specifically stable-isotope labelled L-glutamic acid and 2-oxoglutaric acid

Cappon, J. J.,Baart, J.,Walle, G. A. M. van der,Raap, J.,Lugtenburg, J.

, p. 158 - 166 (2007/10/02)

(3-13C)-(4-13C)-,(5-13C)- and (3,4-13C2)-2-oxoglutaric acid were prepared starting from the simple 13C-enriched compounds: ethyl bromoacetate and paraformaldehyde, via a single reaction scheme on the gram scale in high yield.This reaction scheme allows specific 13C enrichment of every carbon position and any combination of positions. (3-13C)-,(4-13C)-, (5-13C), (3,4-13C2) and (15N)-L-glutamic acid were prepared by converting the corresponding 2-oxoglutaric acids via an enantioselective enzymatic conversion.The labelled L-glutamic acids and 2-oxoglutaric acids were characterized by 1H NMR, 13C NMR and mass spectrometry.

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