115473-68-2

Basic information

• Product Name: 4-[(1E)-2-(4,4-dimethyl-3,4-dihydro-2H-thiochromen-7-yl)prop-1-en-1-yl]benzoic acid
• Synonyms: benzoic acid, 4-[(1E)-2-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-yl)-1-propen-1-yl]-
• CAS NO: 115473-68-2
• Molecular Formula: C₂₁H₂₂O₂S
• Molecular Weight: 338.4632
• Mol File: 115473-68-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 496.6°C at 760 mmHg
• Flash Point: 254.1°C
• Density: 1.168g/cm³
• Vapor Pressure: 1.11E-10mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 4-[(1E)-2-(4,4-dimethyl-3,4-dihydro-2H-thiochromen-7-yl)prop-1-en-1-yl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1E)-2-(4,4-dimethyl-3,4-dihydro-2H-thiochromen-7-yl)prop-1-en-1-yl]benzoic acid(115473-68-2)
• EPA Substance Registry System: 4-[(1E)-2-(4,4-dimethyl-3,4-dihydro-2H-thiochromen-7-yl)prop-1-en-1-yl]benzoic acid(115473-68-2)

Safety Data

• Hazardous Substances Data: 115473-68-2(Hazardous Substances Data)

Relevant articles and documents

Condensed heterocyclic compounds

The invention relates to compounds of the formula STR1 wherein R1 is hydrogen, acyl, lower-alkyl or --CHO, --CH2 OR10, --COR7 or OR13 ; R2, R3 and R4 are, independently, hydrogen, lower-alkyl, lower-alkoxy or halogen; R5 and R6 are, independently, hydrogen or lower-alkyl; R7 is hydroxy, lower-alkoxy or NR8 R9 ; R8 and R9 are, independently, hydrogen or lower-alkyl; X and Y are, independently, >CR14 R15, --O--, --S--, >SO, >SO2 or >NR18 ; R10 and R18 are, independently, hydrogen, lower-alkyl or acyl; M is --C(R11)=C(R12)--, --CONH-- or --NH--CO--; R11, R12, R14 and R15 are, independently, hydrogen or lower-alkyl, R13 is hydrogen, lower-alkoxycarbonyl or lower- alkyl, which can be substituted by amino, mono-alkylamino, di-alkylamino, morpholino, thiomorpholino or piperazino; and n is 1, 2, 3 or 4; with the proviso that at least one of X and Y comprises a hetero atom and n is 1, 3 or 4 when X contains a hetero atom, Y is >C(CH3)2 and R1 is lower-alkyl or --CH2 OR10 or --COR7, or a salt of a compound of formula I, when R1 is carboxy. The compounds of formula I are useful in the treatment of prophylaxis of neoplasms, dermatoses and ageing of the skin.