115476-19-2Relevant academic research and scientific papers
FLUORINE-CONTAINING AMINO ACIDS. III. α-TRIFLUOROMETHYL AMINO ACIDS
Soloshonok, V. A.,Gerus, I. I.,Yagupol'skii, Yu. L.,Kukhar', V. P.
, p. 2034 - 2038 (2007/10/02)
A convenient method was developed for the synthesis of α-trifluoromethyl amino acids by the alkylation of the previously unknown imines of methyl 3,3,3-trifluoropyruvate with organometallic reagents.The differences in the reactivity of the imines in relation to the substituent at the nitrogen atom were demonstrated.
