115479-63-5

Upstream product

• 108-24-7 acetic anhydride 
• 115479-61-3 dimethyl <3α,4α-bis(benzyloxy)-5β-hydroxytetrahydro-2H-pyran-2β-yl>malonate 
• 53996-40-0 3,4-bis(benzoloxy)furan 
• 115479-57-7 dimethyl 3-exo-acetoxy-5,6-endo-bis(benzyloxy)-7-oxabicyclo<2.2.1>heptane-2,2-dicarboxylate 
• 115479-55-5 dimethyl 6-exo-acetoxy-2,3-bis(benzyloxy)-7-oxabicyclo<2.2.1>hept-2-ene-5,5-dicarboxylate 

Relevant academic research and scientific papers

Highly Stereoselective Total Synthesis of β-Ribofuranosylmalonate

β-Ribofuranosylmalonates, prospective synthons for a variety of C-nucleosides, have been synthesized stereoselectively through the high-pressure Diels-Alder reaction of furan with dialkyl (acetoxymethylene)malonate, followed by reductive retrograde aldol C-C bond fission of the diol derived from the adduct.

Diels-Alder Reaction of Dimethyl Acetoxymethylenemalonate with 3,4-Dialkoxyfurans and the Utility of Its Adducts in the Stereospecific Synthesis of Lyxopyranosyl C-Glycosides

Dimethyl lyxopyranosylmalonates were synthesized in stereospecific manner from the adducts obtained from Diels-Alder reaction of 3,4-dialkoxyfurans and dimethyl acetoxymethylenemalonate, through retrograde aldol C-C bond fission under reductive condition as a key step.