115483-80-2Relevant academic research and scientific papers
Heterocyclic β-Enamino Esters, 49. - Furoquinazolines, Furophthalazine, and Adducts with 4-Phenyl-1,2,4-triazoline-3,5-dione to Benzofurans, Indoles, and Benzothiophenes
Wamhoff, Heinrich,Fassbender, Franz-Josef,Nieger, Martin
, p. 2157 - 2162 (2007/10/02)
The tetrahydrobenzofurans 1a-e, the indole 2, and the benzothiophene 3 afford with 4-phenyl-1,2,4-triazoline-3,5-dione the adducts 4a-e, 5, and 6.With phenyl or tolyl isocyanate, 1a, b give via the carbodiimides A with alcohols the isoureas 10a-d.In the presence of primary amines, the intermediary guanidines B cyclize to give the novel furoquinazolines 11a-c.The structure of 11a is established by X-ray diffraction. 1c forms with hydrazine hydrate the novel furophthalazine 12.
