115494-60-5Relevant academic research and scientific papers
NM 283, an efficient prodrug of the potent anti-HCV agent 2′-C-methylcytidine
Pierra,Benzaria,Amador,Moussa,Mathieu,Storer,Gosselin
, p. 767 - 770 (2005)
In order to improve the oral bioavailability of 2′-C-methylcytidine, a potent anti-HCV agent, the corresponding 3′-O-L-valinyl ester derivative (NM 283) has been synthesized. Based on its ease of synthesis and its physicochemical properties, NM 283 has emerged as a promising antiviral drug for treatment of chronic HCV infection. Copyright Taylor & Francis, Inc.
