1155-74-4

Basic information

• Product Name: 1-tetradecylpyridinium bromide
• Synonyms: 1-tetradecylpyridinium bromide;Myristyl-Pyridinium Bromide;PYRIDINIUM,1-TETRADECYL,BROMIDE;1-Myristylpyridinium·bromide;1-myristylpyridin-1-ium bromide;1-tetradecylpyridin-1-ium bromide;1-Tetradecylpyridin-1-iuM broMide, 95+%
• CAS NO: 1155-74-4
• Molecular Formula: Br*C₁₉H₃₄N
• Molecular Weight: 356.38396
• EINECS: 214-586-2
• Mol File: 1155-74-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 65-67 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-tetradecylpyridinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tetradecylpyridinium bromide(1155-74-4)
• EPA Substance Registry System: 1-tetradecylpyridinium bromide(1155-74-4)

Safety Data

• Hazardous Substances Data: 1155-74-4(Hazardous Substances Data)

Usage

General Description

1-Tetradecylpyridinium bromide, also known as TDPB, is a quaternary ammonium compound with the chemical formula C19H34BrN. It is an organic salt that is commonly used as a surfactant and disinfectant due to its antimicrobial properties. TDPB is used in many personal care and pharmaceutical products, as well as in industrial applications and research settings. It has been shown to have strong antibacterial, antifungal, and antiviral activities, making it a valuable ingredient in a wide range of disinfectant and antiseptic products. TDPB is soluble in water and organic solvents, and its molecular structure allows it to disrupt the cell membranes of microorganisms, effectively killing them. However, TDPB should be handled with care, as it is toxic if ingested or inhaled, and can cause irritation to the skin and eyes.

InChI:InChI=1/C19H34N.BrH/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-18-15-13-16-19-20;/h13,15-16,18-19H,2-12,14,17H2,1H3;1H/q+1;/p-1

Upstream product

• 110-86-1 pyridine 
• 112-71-0 1-Bromotetradecane 

Downstream Products

• 2785-54-8 tetradecylpyridinium chloride 
• 94070-50-5 Tetradecylpyridinium salicylate 

Relevant articles and documents

The Salt-Induced Sphere-Rod Transition of Micelles of 1-Tetradecylpyridinium Bromide in Aqueous NaBr Solutions

Static light scattering from aqueous NaBr solutions of 1-tetradecylpyridinium bromide (TPB) has been measured over the range of NaBr concentrations from 0 to 0.50 mol dm-3 at 25 °C, and the micelle molecular weight has been estimated. For 0 - 0.20 mol dm-3 NaBr, the reduced intensity of scattered light does not show any angular dependence, and the molecular weight of the spherical micelle of TPB slightly increases from 27.6×103 to 41.4×103 with increasing NaBr concentration. Beyond 0,20 mol dm-3 NaBr, the angular dissymmetry of the reduced scattering intensity and a steep increase in the micelle molecular weight from 41.4×103 to 177.8×103 are observed. Therefore, TPB has been considered to form rodlike micelles. The linear double logarithmic relationship between molecular weight and ionic strength holds for spherical and rodlike micelles, respectively. From the intersection of these two lines, the threshold NaBr concentration for the sphere-rod trainsition of TPB micelle is estimated to be 0.19 mol dm-3 where the micelle has a molecular weight of 41.3×103.

Micelle Size in Ethylammonium Nitrate As Determined by Classical and Quasi-Elastic Light Scattering

Aggregation of surfactants to form micelles in ethylammonium nitrate, a low melting fused salt, was investigated by classical and quasi-elastic light scattering.For tetradecylpyridinium bromide and hexadecylpyridinium bromide the following data were obtained: critical micelle concentrations, 8.0E-2 and 2.0E-2 mol kg-1; micellar aggregation numbers, 17 and 26; second virial coefficients, 1.64E-3 and 1.30E-3 mol cm3 g-2; and hydrodynamic radii, 14 and 22 Angstroem, respectively.The results are consistent with either a small classical spherical micelle containing only surfactant or a spherical mixed micelle containing surfactant and ethylammonium ions as a cosurfactant.The measured second virial coefficients are almost equal to those calculated for hard spheres and reflect highly screened electrostatic interactions in the totally ionized solvent.

Structure-activity relationship modeling and experimental validation of the imidazolium and pyridinium based ionic liquids as potential antibacterials of mdr acinetobacter baumannii and staphylococcus aureus

Online Chemical Modeling Environment (OCHEM) was used for QSAR analysis of a set of ionic liquids (ILs) tested against multi-drug resistant (MDR) clinical isolate Acinetobacter baumannii and Staphylococcus aureus strains. The predictive accuracy of regression models has coefficient of determination q2 = 0.66 ? 0.79 with cross-validation and independent test sets. The models were used to screen a virtual chemical library of ILs, which was designed with targeted activity against MDR Acinetobacter baumannii and Staphylococcus aureus strains. Seven most promising ILs were selected, synthesized, and tested. Three ILs showed high activity against both these MDR clinical isolates.

Synthesis, characterization and conductivity of quaternary nitrogen surfactants modified by the addition of a hydroxymethyl substructure on the head group

Two novel series of hydroxymethyl group-appended quaternary nitrogen surfactants (QNSs) based on the aliphatic N-alkyl-trimethylammonium and aromatic N-alkylpyridinium head groups were synthesized from the appropriate nitrogen head group precursor and 1-bromoalkane. The QNSs were characterized using 1H and 13C nuclear magnetic resonance and infrared spectroscopy, and their purity confirmed using elemental analysis. The solution behavior of the QNSs was investigated by conductivity, assessing both the aggregation concentration as well as the amount of counter-ion dissociation. The results showed a general decrease in the aggregation concentration for the compounds with the hydroxymethyl addition, where the pyridinium compounds were more affected than the ammonium QNSs. In contrast, the extent of counter-ion dissociation (α) from the aggregate was slightly increased for the ammonium compounds but that of the pyridinium compounds was not generally affected by the structural modification.