115503-71-4Relevant academic research and scientific papers
Aromatase inhibitors: Synthesis, biological activity, and structure of 1,2-imidazolylmethylcyclopentanol derivatives
Kato,Ikeda,Sugita,Nitta,Enari,Kashima,Konno,Niimura
, p. 2152 - 2158 (2007/10/03)
Two series of 1,2-disubstituted imidazolylmethylcyclopentanol derivatives (5a-d, 10a-d) were prepared by using easily available methyl 2- oxocyclopentanecarboxylate as the starting material. Evaluation of the aromatase inhibitory activities in vitro was p
METHOD FOR INHIBITING AROMATASE
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, (2008/06/13)
This invention provides a method of inhibiting aromatase and treating of estrogen-dependent diseases in a patient by administering azole derivatives as nonsteroidal inhibitors. The azole derivative has the formula where R1 a is hydrogen or a (C1-C5) alkyl
