1155261-03-2Relevant academic research and scientific papers
α-Carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from norrish-type-II reactions
Cai, Xichen,Cygon, Peter,Goldfuss, Bernd,Griesbeck, Axel G.,Heckroth, Heike,Fujitsuka, Mamoru,Majima, Tetsuro
, p. 4662 - 4667 (2006)
Triplet 1,4-biradicals were generated by Norrish-Type-II hydrogen transfer from cx-heteroatom-substituted -branched butyrophenones 1-6 and detected by laser flash absorption measurements. For three oxy-substituted compounds 2-4 (Rα = OH, OCOMe,
Asymmetric synthesis of trans-disubstituted cyclopropanes using phosphine oxides and phosphine boranes
Clarke, Celia,Foussat, Stephanie,Fox, David J.,Pedersen, Daniel Sejer,Warren, Stuart
supporting information; experimental part, p. 1323 - 1328 (2009/12/04)
The stereocontrolled synthesis of trans-disubstituted cyclopropylketones has been achieved from β-alkyl, γ-benzoyl phosphine oxides via a three-step cascade reaction incorporating an acyl transfer, phosphinoyl transfer and cyclisation to form the cyclopropane. Using Evans' chiral oxazolidinone auxiliary and by masking the phosphine oxide moiety as a phosphine borane we have extended the method to the synthesis of enantiomerically-enriched trans-disubstituted cyclopropyl ketones.
